Authors: Gaurav Seth, KG Chengappa, Durga Prasanna Misra, Ramesh Babu, Pooja Belani, KC Shanoj, Gunjan Kumar, Vir Singh Negi

Publication Date: 08/2018

Journal: Rheumatology international

Volume: 38

Issue: 8

Pages: 1495-1501

Publisher: Springer Berlin Heidelberg

Retinopathy in the context of systemic lupus erythematosus (SLE) is associated with severe disease and poorer prognosis. We studied retinopathy in our cohort of Indian lupus patients. Four hundred and thirty-seven patients fulfilling the Systemic Lupus International Collaborating Clinics-American College of Rheumatology-2012 criteria, attending the department of Clinical Immunology were enrolled under this cross-sectional study. A comprehensive clinical (including ophthalmological) examination and immunological profile were performed. Retinopathy was defined if cotton-wool spots, haemorrhages, vasculitis, retinal detachment or optic disc changes as papilledema, optic atrophy were present. Disease activity was assessed using SLE disease activity index (SLEDAI). Mean age of participants was 28.06 ± 9.7 years (93.1% females); median disease duration 12 months (Interquartile range—IQR 6.36 …